Restrict Derailleur Travel
How about the possibility to restrict the travel of the rear derailleur, to make the 12speed only a 9 or 10 speed?
Like for example when you have a mechanical and only can use a certain range of the cassette or what so ever, that you can restrict shifting without touching the limit screws.

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Rob Dixon commented
I like it. Technically, you could use the AXS drivetrain with most 9, 10, 11, 12 spd drivetrains and should be able to do so. I had to adjust my AXS XX1 rear derailleur for my Wahoo Kickr(16). When I hit the trails, I now have to adjust it for my frame/wheel combo. The app should allow profiles that can be applied per setup.
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rick.landry@rogers.com commented
I like this idea. I sometimes ride my AXS Eagle as a singlespeed by shifting to the gear I want then pulling the battery. Limiting shifting with the app would be a more elegant solution.